Gerður Rún Rúnarsdóttir flytur fyrirlestur um verkefni sitt til meistaraprófs í efnafræði. Heiti verkefnisins er: Efnasmíðar og hvarfgirni trípeptíð estera við málmjónir (Synthesis and investigation of reactivity of alkylated tripeptides with metal ions)
Ágrip:
Release of greenhouse gases is a great environmental concern in todays world. Carbon dioxide is the thermodynamic end product of combustion of organic compounds and it is one of the most abundant greenhouse gases. CO2 is known as relatively thermodynamically stable and to have high kinetic barrier.[1] A feasible approach to trap and recycle CO2 from industrial waste in an economical manner is to reduce it to C1 starting materials for the chemical industry such as methanol, methane, or formic acid. Formation of these C1 products is facilitated when metal based catalysts are employed to lower the kinetic barrier and provide a reaction pathway that may occur under ambient conditions.[2][3] The long term vision is to synthesize a biodegradable CO2 copolymer. In the research presented, synthetic methodology for a novel tripeptide, using liquid phase peptide synthesis (LPPS), was completed. The tripeptide was employed as a ligand to form a palladium complex that was characterized. Our approach uses alkylated tripeptides as a ligand that can coordinate to a metal ion forming 5 or 6 membered ring chelates which are also the thermodynamically most stable form of chelation,[4][5][6] and may form a complex that is coordinatively unsaturated. Alkylated glutathione (GSH) was used as a model tripeptide and its reaction with metal ions was investigated.
Leiðbeinendur: Dr. Sigridur G. Suman, dósent við Raunvísindadeild Háskóla Íslands og and dr. Ingvar H. Árnason, prófessor emeritus við Raunvísindadeild Háskóla Íslands.
Prófdómari: Dr. Gissur Örlygsson, verkefnisstjóri hjá Nýsköpunarmiðstöð Íslands